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Paroxetine is a potent and highly selective serotonin reuptake inhibitor SSRI and insurance on weak binding to muscarinic acetylcholine receptorsIn a double-blind, placebo-controlled study involving chronic tinnitus patients, few of whom suffered from depression, the paroxetine group showed little difference from placebo on tinnitus loudness matching, Tinnitus Handicap Questionnaire scores and other measures; however phrase palliative medicine confirm insurance on group showed a significant improvement in tinnitus aggravation compared with the control group Although Insurance on are widely used to treat tinnitusthe authors suggested that antidepressants should not oon used to treat nondepressed tinnitus patients.

However, in a case study, paroxetine significantly reduced tinnitus and improved mood in a patient with severe depression, anxiety and tinnitus In addition to its use as an antidepressant, trazodone is also used to treat insomnia.

Insurance on main side effects are drowsiness and hypotension. Trazodone was evaluated in a prospective, placebo-controlled, double-blind trial involving 83 subjects insurance on approximately half each in the placebo and treatment groups. Patients in both the placebo and insurance on arms showed significant improvement in tinnitus loudness, discomfort and quality of life; however, the differences kn the placebo and trazodone groups were not statistically significant.

Thus, trazodone was not shown to be effective in treating tinnitus using this particular regimen and insurance on this patient population. Vestipitant is a novel antagonist of the tachykinin NK 1 receptor that binds substance P. Substance P acts as a neurotransmitter and neuromodulator.

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